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Journal of Bacteriology, May 2009, p. 3420-3423, Vol. 191, No. 10
0021-9193/09/$08.00+0     doi:10.1128/JB.01672-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Large Intergenic Cruciform-Like Supermotifs in the Lactobacillus plantarum Genome{triangledown} ,{dagger}

Michiel Wels,1,2,3* Roger S. Bongers,1,3 Jos Boekhorst,2 Douwe Molenaar,1,3 Mark Sturme,4 Willem M. de Vos,1,4 Roland J. Siezen,1,2,3 and Michiel Kleerebezem1,3,4

TI Food and Nutrition, Wageningen, The Netherlands,1 Radboud University Nijmegen-Medical Centre/NCMLS, Nijmegen, The Netherlands,2 NIZO Food Research, Ede, The Netherlands,3 Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands4

Received 28 November 2008/ Accepted 5 March 2009

Twenty-four Lactobacillus plantarum supermotifs (LPSMs) with lengths from ~800 to 1,000 nucleotides were identified in the L. plantarum genome. LPSMs were conserved in other L. plantarum strains but not in other species. Secondary structure analysis predicted that LPSMs may fold into cruciform-like structures. Preliminary experiments indicate that the LPSMs are transcribed.

* Corresponding author. Mailing address: NIZO Food Research BV, P.O. Box 20, 6710 BA, Ede, The Netherlands. Phone: 31 318 659 511. Fax: 31 318 650 400. E-mail: michiel.wels{at}nizo.nl

{triangledown} Published ahead of print on 13 March 2009.

{dagger} Supplemental material for this article may be found at http://jb.asm.org/.

Journal of Bacteriology, May 2009, p. 3420-3423, Vol. 191, No. 10
0021-9193/09/$08.00+0     doi:10.1128/JB.01672-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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