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Journal of Bacteriology, August 2009, p. 5320-5324, Vol. 191, No. 16
0021-9193/09/$08.00+0     doi:10.1128/JB.00522-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

A Critical Process Controlled by MalT and OmpR Is Revealed through Synthetic Lethality {triangledown}

Sylvia A. Reimann and Alan J. Wolfe*

Department of Microbiology and Immunology, Loyola University Chicago, 2160 S. First Ave., Bldg. 105, Maywood, Illinois 60153

Received 17 April 2009/ Accepted 2 June 2009

The death of cells harboring defects in two distinct pathways implicates these pathways in the control of an essential process. Here we report that cells lacking OmpR and harboring constitutively active MalT undergo premature death that involves increased expression of the outer membrane porin LamB.

* Corresponding author. Mailing address: Department of Microbiology and Immunology, Loyola University Chicago, 2160 S. First Ave., Bldg. 105, Maywood, IL 60153. Phone: (708) 216-5814. Fax: (708) 216-9574. E-mail: awolfe{at}lumc.edu

{triangledown} Published ahead of print on 5 June 2009.

Journal of Bacteriology, August 2009, p. 5320-5324, Vol. 191, No. 16
0021-9193/09/$08.00+0     doi:10.1128/JB.00522-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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