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J Bacteriol. 1961 August; 82(2): 247-251
Copyright ©, 1961, The Williams & Wilkins Company. All Rights Reserved.

INHIBITION OF ALGAE BY NYSTATIN

Institute of Microbiology, Rutgers, The State University, New Brunswick, New Jersey

ABSTRACT

LAMPEN, J. O. (Rutgers, the State University, New Brunswick, N. J.), AND PETER ARNOW. Inhibition of algae by nystatin. J. Bacteriol. 82:247–251. 1961.—The polyenic antibiotic nystatin inhibited the growth of a broad range of algae at concentrations of 1 to 30 µg per ml. Organisms included in the Chlorophyta, Euglenophyta, Chrysophyta, and Cyanophyta were inhibited, but a Bacillariophyceae was insensitive. Nystatin was lethal at concentrations which completely prevented growth. The polyene was absorbed by sensitive algae from aqueous medium. Nystatin produced K⁺ leakage, but did not inhibit dark respiration or photosynthetic oxygen production. The effects of the antibiotic on algae appear to be similar in many ways to those on yeast.