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J Bacteriol. 1961 December; 82(6): 898-904
Copyright © 1961, The Williams & Wilkins Company. All Rights Reserved.

INDUCTION AND REPRESSION OF NITRATE REDUCTASE IN NEUROSPORA CRASSA

Stephen C. Kinsky

Department of Pharmacology, Washington University School of Medicine, St. Louis, Missouri

ABSTRACT

KINSKY, STEPHEN C. (Washington University, St. Louis, Mo.). Induction and repression of nitrate reductase in Neurospora crassa. J. Bacteriol. 82:898–904. 1961.—Techniques are described for studying induced enzyme formation in Neurospora crassa. The effects of various parameters (time, pH, nitrate concentration, etc.) on the induction of nitrate reductase were investigated. It was demonstrated that NH4+, which is the end product of the metabolic sequence initiated by nitrate reductase, repressed formation of the enzyme. Parallel to the formation of nitrate reductase there was an increase in reduced triphosphopyridine nucleotide (TPNH)-cytochrome c reductase activity. The relationship of these two activities to each other and to the constitutive TPNH-cytochrome c reductase present in noninduced mycelia is discussed.

J Bacteriol. 1961 December; 82(6): 898-904
Copyright © 1961, The Williams & Wilkins Company. All Rights Reserved.



This article has been cited by other articles:

  • Filner, P., Varner, J. E., Wray, J. L. (1969). Environmental or developmental changes cause many enzyme activities of higher plants to rise or fall. Science 165: 358-367  


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