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J Bacteriol. 1962 April; 83(4): 828-836
Copyright © 1962, The Williams & Wilkins Company. All Rights Reserved.

A MUTANT OF A SCOTOCHROMOGENIC MYCOBACTERIUM DETECTED BY COLONY MORPHOLOGY AND LIPID STUDIES

Department of Medical Microbiology, University of Wisconsin, Madison, Wisconsin
Randall Laboratory of Physics, The University of Michigan, Ann Arbor, Michigan

ABSTRACT

FREGNAN, G. B. (University of Wisconsin, Madison), D. W. SMITH, AND H. M. RANDALL. A mutant of a scotochromogenic Mycobacterium detected by colony morphology and lipid studies. J. Bacteriol. 83:828–836. 1962.—A variant of a scotochromogenic strain of Mycobacterium is described. This mutant was recognized by studies of colony morphology and lipid content. Mycoside D was shown to be present in the smooth-Sy variety but absent in the rough-Ry variety. The rough-Ry variety appeared spontaneously from smooth-Sy, or by induction after prolonged incubation in a synthetic liquid medium or exposure to ultraviolet irradiation. This mutation is not reversible.

¹ Present address: Istituto di Microbiologia, Universitá di Bologna, Bologna, Italy.

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