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J Bacteriol. 1962 May; 83(5): 1037-1041
Copyright © 1962, The Williams & Wilkins Company. All Rights Reserved.

BASES OF THE NUCLEIC ACID OF FOWLPOX VIRUS AND HOST DEOXYRIBONUCLEIC ACID

^a Department of Microbiology, University of Mississippi School of Medicine, Jackson, Mississippi

ABSTRACT

RANDALL, CHARLES C. (University of Mississippi School of Medicine, Jackson), LANELLE G. GAFFORD, AND ROBERT W. DARLINGTON. Bases of the nucleic acid of fowlpox virus and host deoxyribonucleic acid. J. Bacteriol. 83:1037–1041. 1962.—The nucleic acid of fowlpox virus obtained from purified inclusions was identified as deoxyribonucleic acid (DNA). The base ratios determined on whole virus and on isolated DNA were practically identical. The molar ratios of purines to pyrimidines were approximately unity. The ratio of adenine plus thymine to guanine plus cytosine was 1.8.

The base ratios of DNA obtained from chick red cells were approximately the same as other animal DNA preparations reported in the literature. It is of interest that the molar proportions of host DNA are significantly different from viral DNA.

¹ Predoctoral Trainee at the University of Mississippi School of Medicine on training grant 2E-69, from the National Institute of Allergy and Infectious Disease, U.S. Public Health Service.