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J Bacteriol. 1962 November; 84(5): 1011-1015
Copyright © 1962, The Williams & Wilkins Company. All Rights Reserved.

SIMPLIFIED ANTISTREPTOCOCCAL DEOXYRIBONUCLEASE ASSAY¹

^a Bio-Science Laboratories, Los Angeles, California

ABSTRACT

OLITZKY, IRVING (Bio-Science Laboratories, Los Angeles, Calif.), SAM BERKMAN, AND DORIS BASS. Simplified antistreptococcal deoxyribonuclease assay. J. Bacteriol. 84:1011–1015. 1962.—A simple antistreptococcal deoxyribonuclease assay has been devised in which dilutions of the patient's serum are reacted with deoxyribonuclease, and residual active enzyme is then detected by the Di Salvo technique using commercially available agar medium containing deoxyribonucleic acid. Use of this test as supplemental to antistreptolysin-O titrations leads to increased positive findings when searching for streptococcal antibodies.

¹ This work was presented in part at the 62nd Annual Meeting of the American Society for Microbiology, Kansas City, Mo., May, 1962.