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J Bacteriol. 1963 May; 85(5): 1028-1031
Copyright © 1963, The Williams & Wilkins Company. All Rights Reserved.

ACTION OF FORMALDEHYDE ON MICROORGANISMS I.

Correlation of Activity with Formaldehyde Metabolism

Biochemical Research Laboratory, The Dow Chemical Company, Midland, Michigan

ABSTRACT

NEELY, W. BROCK (The Dow Chemical Co., Midland, Mich.). Action of formaldehyde on microorganisms. I. Correlation of activity with formaldehyde metabolism. J. Bacteriol. 85:1028–1031. 1963.—The action of formaldehyde in concentrations sublethal for the culture appeared to be at least twofold. The first phase caused a drop in viability, followed by a second phase where bacteriostatic conditions existed. During both these intervals, formaldehyde was being metabolized. As soon as the organism had lowered the formaldehyde concentration to a critical level, the normal growth cycle was resumed, with a resultant increase in cell population.