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CHIMPANZEE KIDNEY TISSUE CULTURES FOR GROWTH AND ISOLATION OF VIRUSES

Department of Preventive Medicine, University of Wisconsin Medical School, Madison, Wisconsin

ABSTRACT

DICK, ELLIOT C. (University of Wisconsin, Madison). Chimpanzee kidney tissue cultures for growth and isolation of viruses. J. Bacteriol. 86:573–576. 1963.—Chimpanzee kidney tissue cultures were employed for propagation of several laboratory strains of viruses that commonly inhabit the respiratory and intestinal tracts, or both, and for isolation of viruses from throat washings of persons with common colds and tonsillitis-pharyngitis. This tissue culture host was found to support the growth of approximately the same viruses as do Rhesus monkey kidney tissue cultures, with two exceptions: (i) chimpanzee kidney tissue culture was much more susceptible to herpes simplex infection, and (ii) cytopathic effects were not produced by either "M" or "H" strains of muriviruses (common cold viruses). The presence of adventitious viruses in some uninoculated chimpanzee kidney tissue cultures is suspected.