This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wallace, B. J. Articles by Pittard, J. Search for Related Content PubMed PubMed Citation Articles by Wallace, B. J. Articles by Pittard, J.

Genetic and Biochemical Analysis of the Isoenzymes Concerned in the First Reaction of Aromatic Biosynthesis in Escherichia coli

School of Microbiology, University of Melbourne, Parkville, Victoria, Australia

ABSTRACT

Mutant strains of Escherichia coli K-12 were isolated possessing mutations which affected the tyrosine-inhibitable 3-deoxy-D-arabinoheptulosonic acid-7-phosphate (DAHP) synthetase, the phenylalanine-inhibitable DAHP synthetase, or the tryptophan-repressible DAHP synthetase. The mutations causing the loss of each of these activities have been mapped and are widely separated from each other on the E. coli chromosome. Chromatography on diethylaminoethyl cellulose columns allowed the recognition of four peaks of activity.

This article has been cited by other articles:

• Vassiliadis, G., Peduzzi, J., Zirah, S., Thomas, X., Rebuffat, S., Destoumieux-Garzon, D. (2007). Insight into Siderophore-Carrying Peptide Biosynthesis: Enterobactin Is a Precursor for Microcin E492 Posttranslational Modification. Antimicrob. Agents Chemother. 51: 3546-3553 [Abstract] [Full Text]