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J Bacteriol. 1967 October; 94(4): 1075-1081
Copyright © 1967 American Society for Microbiology. All Rights Reserved.

Function of the Glyoxylate-condensing Enzymes I. Growth of Escherichia coli on n-Valeric Acid

Philip Furmanski, Warner S. Wegener, Henry C. Reeves1 and Samuel J. Ajl

a Department of Biochemistry, Research Laboratories, Albert Einstein Medical Center, Philadelphia, Pennsylvania 19141

ABSTRACT

Growth of Escherichia coli E-26 on valeric acid results in the formation of a mutant population characterized by the ability to form constitutively several glyoxylate-condensing enzymes. This mutant also differs from the parent organism in the ability to effect rapid growth on a series of short-chain fatty acids. These mutants were utilized in postulating genetic relationships among the various glyoxylate-condensing activities and also in correlating the presence of these enzymes with the ability of the mutants to initiate growth quickly on short-chain fatty acids.


FOOTNOTES

1 Research Career Development Awardee (5-K3-AI-6928) from the National Institutes of Health.


J Bacteriol. 1967 October; 94(4): 1075-1081
Copyright © 1967 American Society for Microbiology. All Rights Reserved.







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