Authors' Corrections for Osorio et al., J. Bacteriol. 186 (15) 5167-5171.
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Journal of Bacteriology, December 2004, p. 8549, Vol. 186, No. 24
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.24.8549.2004

AUTHOR'S CORRECTION

The ompU Paralogue vca1008 Is Required for Virulence of Vibrio cholerae

Carlos G. Osorio, Hector Martinez-Wilson, and Andrew Camilli

Tufts University Medical School, Tufts University, Boston, Massachusetts 02111, and Programa de Microbiología y Micología, Facultad de Medicina, Universidad de Chile, Santiago, Chile

Volume 186, no. 15, p. 5167-5171, 2004. Due to an illegitimate recombination event, the triple porin mutant ({Delta}ompU {Delta}ompT {Delta}vc0972) we reported is still UmpU+. The correct strain has been constructed and exhibits different phenotypes than what was reported. It grows in LB broth with a similar doubling time and final cell density as the parent strain, GOA1264 (OmpU+ OmpT+ VC0972+). However, it is outcompeted by GOA1264 ~200-fold in a competition in LB broth at 37°C after 16 generations and is outcompeted 3-fold in competition in infant mice. In addition, the outer membrane protein profile of the triple mutant is indistinguishable from that of the {Delta}ompU single and {Delta}vca1008 {Delta}ompU double mutants.

Journal of Bacteriology, December 2004, p. 8549, Vol. 186, No. 24
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.24.8549.2004





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