A Protein from a Parasitic Microorganism, Rickettsia prowazekii, Can Cleave the Signal Sequences of Proteins Targeting Mitochondria
J. Bacteriol. Kitada et al.
189: 844
Supplemental material
Files in this Data Supplement:
- Supplemental file 1 -
Table S1, MPP-homologous genes in archaeal and eubacterial genomes; Fig. S1, Expression and purification of RPP; Fig. S2, HPLC analyses of peptide cleavage activity of RPP; Fig. S3, action of RPP on basic proteins; Fig. S4, HPLC analyses of presequence peptide cleavage by RPP; Fig. S5, HPLC analyses of pre-MDH peptide cleavage by RPP and its mutant; Fig. S6, evolution of MPP from a progenitor peptidase in an ancient parasite.
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