This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Goldstein, I. J. Articles by Misaki, A. Search for Related Content PubMed PubMed Citation Articles by Goldstein, I. J. Articles by Misaki, A.

 Previous Article  |  Next Article 

J Bacteriol. 1970 August; 103(2): 422-425
Copyright © 1970 American Society for Microbiology. All Rights Reserved.

Interaction of Concanavalin A with an Arabinogalactan from the Cell Wall of Mycobacterium bovis

Department of Biological Chemistry, The University of Michigan, Ann Arbor, Michigan 48104
The Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan

ABSTRACT

The arabinogalactan isolated from the cell wall of Mycobacterium bovis reacts to form a precipitate with concanavalin A, the phytohemagglutinin of the jack bean. A typical precipitin-like curve is obtained when increasing amounts of the polysaccharide are added to a constant quantity of concanavalin A. Inhibitor studies suggest that concanavalin A reacts with the arabinogalactan by interacting with the C-2, C-3, and C-5 hydroxyl groups of the -D-arabinofuranosyl residues situated at the chain ends of this polysaccharide.

This article has been cited by other articles:

• Sharon, N., Lis, H. (1972). Lectins: Cell-Agglutinating and Sugar-Specific Proteins. Science 177: 949-959