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J Bacteriol. 1972 August; 111(2): 447-453
Copyright © 1972 American Society for Microbiology. All Rights Reserved.

Cell Division and Prophage Induction in Escherichia coli: Effects of Pantoyl Lactone and Various Furan Derivatives

^a Department of Biochemistry, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106

ABSTRACT

Strain T-44 is a thermosensitive mutant of Escherichia coli in which both cell division and prophage repression are altered at elevated temperatures. The effects of various ribosides, pantoyl lactone, and the furfural derivatives nitrofurazone and 5-methyl furfural suggest that some low-molecular-weight compound is important in the control of cell division and prophage repression in this strain. This low-molecular-weight compound may have a five-membered oxygen-containing ring as part of its structure.

¹ Present address: Department of Biochemistry, Temple University, Philadelphia Pa. 19140.

² Present address: Department of Biochemistry, Howard University, Washington, D.C. 20001.