This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sarubbi, F A
Right arrow Articles by Lewis, E
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sarubbi, F A, Jr
Right arrow Articles by Lewis, E

 Previous Article  |  Next Article 

J Bacteriol. 1975 November; 124(2): 750-756

Loss of low-level antibiotic resistance in Neisseria gonorrhoeae due to env mutations.

F A Sarubbi Jr, P F Sparling, E Blackman and E Lewis

ABSTRACT

Mutations (env) which resulted in increased sensitivity of gonococci to diverse compounds were studied by transformation. Strains carrying an env mutation were more sensitive than wild-type strains to several antibiotics, dyes, and detergents. The env mutations resulted in complete phenotypic suppression of low-level resistance to these same drugs determined by mutation at ery. Recombination was observed in transformation crosses between various env mutants. The env locus was not linked to the cluster of antibiotic resistance genes near str and spc.

J Bacteriol. 1975 November; 124(2): 750-756




This article has been cited by other articles:

  • Rouquette-Loughlin, C. E., Balthazar, J. T., Shafer, W. M. (2005). Characterization of the MacA-MacB efflux system in Neisseria gonorrhoeae. J Antimicrob Chemother 56: 856-860 [Abstract] [Full Text]  
  • Rouquette-Loughlin, C., Dunham, S. A., Kuhn, M., Balthazar, J. T., Shafer, W. M. (2003). The NorM Efflux Pump of Neisseria gonorrhoeae and Neisseria meningitidis Recognizes Antimicrobial Cationic Compounds. J. Bacteriol. 185: 1101-1106 [Abstract] [Full Text]  
  • Olesky, M., Hobbs, M., Nicholas, R. A. (2002). Identification and Analysis of Amino Acid Mutations in Porin IB That Mediate Intermediate-Level Resistance to Penicillin and Tetracycline in Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 46: 2811-2820 [Abstract] [Full Text]  
  • Shafer, W. M., Qu, X.-D., Waring, A. J., Lehrer, R. I. (1998). Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family. Proc. Natl. Acad. Sci. USA 95: 1829-1833 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»