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J Bacteriol. 1991 July; 173(14): 4530-4532
Copyright © 1991, American Society for Microbiology. All Rights Reserved.

research-article

Penicillin-Binding Protein 2 Is Essential for the Integrity of Growing Cells of Escherichia coli ponB Strains

Francisco García Del Portillo and Miguel A. De Pedro*

Centro de Biología Molecular, Consejo Superior de Investigaciones Científicas, Facultad de Ciencias, Universidad Autónoma de Madrid, Campus de Cantoblanco, E-28049 Madrid, Spain

ABSTRACT

Analysis of Escherichia coli pbpA(Ts) or rodA(Ts) strains defective for penicillin-binding protein (PBP) 1A or PBP 1B indicated that the activity of PBP 2 is essential to prevent cell lysis in PBP 1B– strains and suggested that PBP 2 is active or activatable in rodA(Ts) mutants under restrictive conditions.

FOOTNOTES

* Corresponding author.

J Bacteriol. 1991 July; 173(14): 4530-4532
Copyright © 1991, American Society for Microbiology. All Rights Reserved.



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