This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Setlow, B.
Right arrow Articles by Setlow, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Setlow, B.
Right arrow Articles by Setlow, P.

 Previous Article  |  Next Article 

J. Bacteriol., Jul 1995, 4149-4151, Vol 177, No. 14
Copyright © 1995, American Society for Microbiology

Binding to DNA protects alpha/beta-type, small, acid-soluble spore proteins of Bacillus and Clostridium species against digestion by their specific protease as well as by other proteases

B Setlow and P Setlow
Department of Biochemistry, University of Connecticut Health Center, Farmington 06030, USA.

Binding of alpha/beta-type, small, acid-soluble proteins from Bacillus subtilis and Clostridium bifermentans to DNA protected these proteins against cleavage by their specific protease (GPR) as well as by trypsin and chymotrypsin. These data suggest that alpha/beta-type, small, acid- soluble protein binding to DNA (i) may result in a structural change in these proteins, giving a more compact protein structure, and (ii) may be important in slowing the degradation of these proteins by GPR, in particular during sporulation.


This article has been cited by other articles:

  • Setlow, B., Atluri, S., Kitchel, R., Koziol-Dube, K., Setlow, P. (2006). Role of Dipicolinic Acid in Resistance and Stability of Spores of Bacillus subtilis with or without DNA-Protective {alpha}/{beta}-Type Small Acid-Soluble Proteins. J. Bacteriol. 188: 3740-3747 [Abstract] [Full Text]  
  • Newcombe, D. A., Schuerger, A. C., Benardini, J. N., Dickinson, D., Tanner, R., Venkateswaran, K. (2005). Survival of Spacecraft-Associated Microorganisms under Simulated Martian UV Irradiation. Appl. Environ. Microbiol. 71: 8147-8156 [Abstract] [Full Text]  
  • Kosman, J., Setlow, P. (2003). Effects of Carboxy-Terminal Modifications and pH on Binding of a Bacillus subtilis Small, Acid-Soluble Spore Protein to DNA. J. Bacteriol. 185: 6095-6103 [Abstract] [Full Text]  
  • Hayes, C. S., Setlow, P. (2001). An {alpha}/{beta}-Type, Small, Acid-Soluble Spore Protein Which Has Very High Affinity for DNA Prevents Outgrowth of Bacillus subtilis Spores. J. Bacteriol. 183: 2662-2666 [Abstract] [Full Text]  
  • Hayes, C. S., Setlow, P. (1998). Identification of Protein-Protein Contacts between alpha /beta -Type Small, Acid-soluble Spore Proteins of Bacillus Species Bound to DNA. J. Biol. Chem. 273: 17326-17332 [Abstract] [Full Text]  
  • Hayes, C. S., Peng, Z.-Y., Setlow, P. (2000). Equilibrium and Kinetic Binding Interactions between DNA and a Group of Novel, Nonspecific DNA-binding Proteins from Spores of Bacillus and Clostridium Species. J. Biol. Chem. 275: 35040-35050 [Abstract] [Full Text]  
  • Hayes, C. S., Alarcon-Hernandez, E., Setlow, P. (2001). N-terminal Amino Acid Residues Mediate Protein-Protein Interactions between DNA-bound alpha /beta -Type Small, Acid-soluble Spore Proteins from Bacillus Species. J. Biol. Chem. 276: 2267-2275 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»