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J. Bacteriol., Oct 1995, 6001-6004, Vol 177, No. 20
Copyright © 1995, American Society for Microbiology

Synergistic induction of the heat shock response in Escherichia coli by simultaneous treatment with chemical inducers

TK Van Dyk, TR Reed, AC Vollmer and RA LaRossa
DuPont Company, Wilmington, Delaware 19880-0173, USA.

Escherichia coli strains carrying transcriptional fusions of four sigma 32-controlled E. coli heat shock promoters to luxCDABE or lacZ reporter genes were stressed by chemicals added singly or in pairs. Much more than additive induction resulted from combinations of cadmium chloride, copper sulfate, ethanol, formamide, 4-nitrophenol, and pentachlorophenol.


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