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J. Bacteriol., 02 1995, 854-857, Vol 177, No. 3
Copyright © 1995, American Society for Microbiology

Regulated expression of the histidase structural gene in Streptomyces griseus

PC Wu, KV Srinivasan and KE Kendrick
Department of Microbiology, Ohio State University, Columbus 43210.

The histidase structural gene from Streptomyces griseus was expressed from a leaderless, monocistronic transcript. Multiple copies of the DNA located upstream of the hutH transcription initiation site led to a significant level of histidase activity when present in trans in the wild-type strain grown under noninducing conditions.


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