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J. Bacteriol., 06 1997, 4046-4048, Vol 179, No. 12
Copyright © 1997, American Society for Microbiology

Identification of the ahp operon of Salmonella typhimurium as a macrophage-induced locus

KP Francis, PD Taylor, CJ Inchley and MP Gallagher
Division of Biology, University of Edinburgh, Scotland.

Previously, we tagged a macrophage-induced Salmonella typhimurium locus with Mudlux (K. P. Francis and M. P. Gallagher, Infect. Immun. 61:640- 649, 1993). The insertion lies within the OxyR-regulated ahpC locus and conveys alkyl peroxide sensitivity. Plasmid-encoded ahp reverses sensitivity but reduces luminescence. This suggests that OxyR is titrated by the multicopy ahp promoter.


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