J. Bacteriol., Sep 1997, 5648-5653, Vol 179, No. 17
EY Huang, AM Mohler and CE Rohlman
Interruption of folate metabolism by trimethoprim results in the elevated
expression of folate stress proteins in Escherichia coli. E. coli grown in
culture medium supplemented with the folate-dependent metabolites glycine,
methionine, and the purine nucleoside inosine shows reduced expression of
folate stress proteins. The folate stress proteins include the universal
stress protein, the ferric uptake regulatory repressor, and possibly,
lipoamide dehydrogenase, the L protein component of the glycine cleavage
enzyme complex.
Copyright © 1997, American Society for Microbiology
Protein expression in response to folate stress in Escherichia coli
Department of Chemistry, Pomona College, Claremont, California 91711, USA.
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