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J. Bacteriol., Sep 1997, 5951-5955, Vol 179, No. 18
Copyright © 1997, American Society for Microbiology

Testosterone-regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni

E Mobus, M Jahn, R Schmid, D Jahn and E Maser
Department of Pharmacology and Toxicology, Philipps University, Marburg, Germany.

The effect of testosterone as the sole carbon source on protein expression was analyzed in Comamonas testosteroni. Testosterone simultaneously induced the expression of steroid- and aromatic hydrocarbon-catabolizing enzymes and repressed one amino acid-degrading enzyme. It is suggested that steroids play a regulative role in catabolic enzyme synthesis during adaptive growth of C. testosteroni.


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