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J. Bacteriol., 11 1997, 7156-7160, Vol 179, No. 22
ME Gallardo, A Ferrandez, V De Lorenzo, JL Garcia and E Diaz
The dsz biodesulfurization cluster from Rhodococcus erythropolis IGTS8 has
been engineered under the control of heterologous broad-host-range
regulatory signals to alleviate the mechanism of sulfur repression, and it
was stably inserted into the chromosomes of different Pseudomonas strains.
The recombinant bacteria were able to desulfurize dibenzothiophene more
efficiently than the native host. Furthermore, these new biocatalysts
combine relevant industrial and environmental traits, such as production of
biosurfactants, with the enhanced biodesulfurization phenotype.
Copyright © 1997, American Society for Microbiology
Designing recombinant Pseudomonas strains to enhance biodesulfurization
Departamento de Microbiologia Molecular, Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Madrid, Spain.
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