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J. Bacteriol., Mar 1997, 2081-2085, Vol 179, No. 6
Copyright © 1997, American Society for Microbiology

Homology with a repeated Yersinia pestis DNA sequence IS100 correlates with pesticin sensitivity in Yersinia pseudotuberculosis

KA McDonough and JM Hare
David Axelrod Institute, Wadsworth Center, New York State Department of Health, Albany 12201-2002, USA. kathleen.mcdonough@wadsworth.org

We have identified IS100 sequences in a specific subset of Yersinia pseudotuberculosis isolates that were also sensitive to the Y. pestis- produced bacteriocin, pesticin. In contrast, Y. pseudotuberculosis strains which did not contain IS100 sequences were not sensitive to pesticin. We propose that IS100 serves as a molecular marker that identifies a subset of Y. pseudotuberculosis isolates that have a particularly close evolutionary and/or ecological relationship with Y. pestis.


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