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Journal of Bacteriology, January 1999, p. 675-680, Vol. 181, No. 2
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
Identification of SycN, YscX, and YscY, Three
New Elements of the Yersinia Yop Virulon
Maite
Iriarte and
Guy R.
Cornelis*
Microbial Pathogenesis Unit, Christian de
Duve Institute of Cellular Pathology and Faculté de
Médecine, Université Catholique de Louvain, B-1200
Brussels, Belgium
Received 4 August 1998/Accepted 28 October 1998
The Yop virulon allows Yersinia spp. to resist the
immune response of the host by injecting harmful proteins into host
cells. We identified three new elements of the Yop virulon: SycN,
required for normal secretion of YopN, and YscX and YscY, two new
components of the secretion machinery.
*
Corresponding author. Mailing address: Microbial
Pathogenesis Unit, Université de Louvain, Avenue Hippocrate, 74, UCL 74.49, B-1200 Brussels, Belgium. Phone: 32 2 764 74 49. Fax: 32 2 764 74 98. E-mail: cornelis{at}mipa.ucl.ac.be.
Journal of Bacteriology, January 1999, p. 675-680, Vol. 181, No. 2
0021-9193/99/$04.00+0
Copyright © 1999, American Society for Microbiology. All rights reserved.
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