This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ormonde, P.
Right arrow Articles by Milton, D. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ormonde, P.
Right arrow Articles by Milton, D. L.

 Previous Article  |  Next Article 

Journal of Bacteriology, April 2000, p. 2326-2328, Vol. 182, No. 8
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Role of Motility in Adherence to and Invasion of a Fish Cell Line by Vibrio anguillarum

Patricia Ormonde,1,dagger Per Hörstedt,2 Ronan O'Toole,1,Dagger and Debra L. Milton1,*

Department of Cell and Molecular Biology1 and Department of Medical Biosciences, Pathology,2 Umeå University, S-901 87 Umeå, Sweden

Received 4 October 1999/Accepted 24 January 2000

To understand further the role of the flagellum of Vibrio anguillarum in virulence, invasive and adhesive properties of isogenic motility mutants were analyzed by using a chinook salmon embryo cell line. Adhesion was unaffected but invasion of the cell line was significantly decreased in nonmotile or partially motile mutants, and the chemotactic mutant was hyperinvasive. These results suggest that active motility aids invasion by V. anguillarum, both in vivo and in vitro.

* Corresponding author. Mailing address: Department of Cell and Molecular Biology, Umeå University, S-901 87 Umeå, Sweden. Phone: 46-90-785 3782. Fax: 46-90-771420. E-mail: Debra.Milton{at}cmb.umu.se.

dagger Present address: Myriad Genetics, Salt Lake City, UT 84108.

Dagger Present address: Department of Biology, Imperial College of Science, Technology, and Medicine, London, England.

Journal of Bacteriology, April 2000, p. 2326-2328, Vol. 182, No. 8
0021-9193/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Meron, D., Efrony, R., Johnson, W. R., Schaefer, A. L., Morris, P. J., Rosenberg, E., Greenberg, E. P., Banin, E. (2009). Role of Flagella in Virulence of the Coral Pathogen Vibrio coralliilyticus. Appl. Environ. Microbiol. 75: 5704-5707 [Abstract] [Full Text]  
  • Moss, A. S., Reddy, N. S., Dortaj, I. M., San Francisco, M. J. (2008). Chemotaxis of the amphibian pathogen Batrachochytrium dendrobatidis and its response to a variety of attractants. Mycologia 100: 1-5 [Abstract] [Full Text]  
  • Larsen, M. H., Blackburn, N., Larsen, J. L., Olsen, J. E. (2004). Influences of temperature, salinity and starvation on the motility and chemotactic response of Vibrio anguillarum. Microbiology 150: 1283-1290 [Abstract] [Full Text]  
  • Stewart, B. J., McCarter, L. L. (2003). Lateral Flagellar Gene System of Vibrio parahaemolyticus. J. Bacteriol. 185: 4508-4518 [Abstract] [Full Text]  
  • Chua, K. L., Chan, Y. Y., Gan, Y. H. (2003). Flagella Are Virulence Determinants of Burkholderia pseudomallei. Infect. Immun. 71: 1622-1629 [Abstract] [Full Text]  
  • Tomich, M., Herfst, C. A., Golden, J. W., Mohr, C. D. (2002). Role of Flagella in Host Cell Invasion by Burkholderia cepacia. Infect. Immun. 70: 1799-1806 [Abstract] [Full Text]  
  • Wang, S.-Y., Lauritz, J., Jass, J., Milton, D. L. (2002). A ToxR Homolog from Vibrio anguillarum Serotype O1 Regulates Its Own Production, Bile Resistance, and Biofilm Formation. J. Bacteriol. 184: 1630-1639 [Abstract] [Full Text]  
  • Tasteyre, A., Barc, M.-C., Collignon, A., Boureau, H., Karjalainen, T. (2001). Role of FliC and FliD Flagellar Proteins of Clostridium difficile in Adherence and Gut Colonization. Infect. Immun. 69: 7937-7940 [Abstract] [Full Text]  
  • Marco-Noales, E., Milan, M., Fouz, B., Sanjuan, E., Amaro, C. (2001). Transmission to Eels, Portals of Entry, and Putative Reservoirs of Vibrio vulnificus Serovar E (Biotype 2). Appl. Environ. Microbiol. 67: 4717-4725 [Abstract] [Full Text]  
  • Lux, R., Miller, J. N., Park, N.-H., Shi, W. (2001). Motility and Chemotaxis in Tissue Penetration of Oral Epithelial Cell Layers by Treponema denticola. Infect. Immun. 69: 6276-6283 [Abstract] [Full Text]  
  • McCarter, L. L. (2001). Polar Flagellar Motility of the Vibrionaceae. Microbiol. Mol. Biol. Rev. 65: 445-462 [Abstract] [Full Text]  
  • Tans-Kersten, J., Huang, H., Allen, C. (2001). Ralstonia solanacearum Needs Motility for Invasive Virulence on Tomato. J. Bacteriol. 183: 3597-3605 [Abstract] [Full Text]  
  • Dietrich, C., Heuner, K., Brand, B. C., Hacker, J., Steinert, M. (2001). Flagellum of Legionella pneumophila Positively Affects the Early Phase of Infection of Eukaryotic Host Cells. Infect. Immun. 69: 2116-2122 [Abstract] [Full Text]  
  • Mathew, J. A., Tan, Y. P., Srinivasa Rao, P. S., Lim, T. M., Leung, K. Y. (2001). Edwardsiella tarda mutants defective in siderophore production, motility, serum resistance and catalase activity. Microbiology 147: 449-457 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»