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Journal of Bacteriology, April 2001, p. 2672-2676, Vol. 183, No. 8
0021-9193/01/$04.00+0   DOI: 10.1128/JB.183.8.2672-2676.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Proteins of Mycobacterium bovis BCG Induced in the Wayne Dormancy Model

Calvin Boon,1 Rong Li,2 Robert Qi,2 and Thomas Dick1,*

Mycobacterium Laboratory1 and Proteomics Laboratory,2 Institute of Molecular and Cell Biology, Singapore 117609, Republic of Singapore

Received 15 November 2000/Accepted 2 February 2001

Oxygen starvation triggers the shiftdown of the obligate aerobe Mycobacterium bovis BCG to a state of dormancy. Two-dimensional electrophoresis showed a drastic up-regulation of the alpha -crystallin homolog, the putative response regulator Rv3133c, and the two conserved hypothetical proteins Rv2623 and Rv2626c in dormant bacilli.

* Corresponding author. Mailing address: Institute of Molecular and Cell Biology, 30 Medical Dr., Singapore 117609, Republic of Singapore. Phone: 65-874-8606. Fax: 65-779-1117. E-mail: mcbtd{at}imcb.nus.edu.sg.

Journal of Bacteriology, April 2001, p. 2672-2676, Vol. 183, No. 8
0021-9193/01/$04.00+0   DOI: 10.1128/JB.183.8.2672-2676.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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