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Journal of Bacteriology, May 2002, p. 2837-2840, Vol. 184, No. 10
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.10.2837-2840.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

The secE Gene of Helicobacter pylori

Claudine Médigue,1,2 Benjamin Chun-Yu Wong,3 Marie Chia-Mi Lin,4 Stéphanie Bocs,2 and Antoine Danchin5*

Génétique des Génomes Bactériens, Institut Pasteur, Paris,1 Génomique Comparative des Micro-organismes Pathogènes, Génopole, Evry, France,2 Department of Medicine,3 Institute of Molecular Biology, University of Hong Kong,4 HKU-Pasteur Research Center, Hong Kong, China5

Received 28 December 2001/ Accepted 6 February 2002

Despite extensive annotation by two independent teams, the Helicobacter pylori genome appeared to lack a complete secretion machinery. The use of clinical isolates to substantiate in silico annotation is used here to identify the missing secE component of the major secretion machinery of Helicobacter pylori.

* Corresponding author. Mailing address: HKU Pasteur Research Centre, Dexter HC Man Building, 8, Sassoon Road, Pokfulam, Hong Kong, China. Phone: 852 2816 8403. Fax: 852 2168 4427. E-mail: adanchin{at}hkucc.hku.hk.

Journal of Bacteriology, May 2002, p. 2837-2840, Vol. 184, No. 10
0021-9193/02/$04.00+0     DOI: 10.1128/JB.184.10.2837-2840.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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