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Journal of Bacteriology, February 2002, p. 1204-1208, Vol. 184, No. 4
0021-9193/01/$04.00+0 DOI: 10.1128/jb.184.4.1204-1208.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.
Genetic Analysis of the RcsC Sensor Kinase from Escherichia coli K-12
D. J. Clarke,1* S. A. Joyce,1 C. M. Toutain,2 A. Jacq,2 and I. B. Holland2
Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom,1
Institut de Genetique et Microbiologie, Universite Paris-Sud, 91405 Orsay Cedex, France2
Received 15 June 2001/
Accepted 19 November 2001
The Rcs two-component pathway is involved in the regulation of capsule production in Escherichia coli. RcsC is predicted to be the sensor component of this two-component pathway, and in this study we present the first genetic data that support the role of RcsC as a hybrid sensor kinase.
* Corresponding author. Mailing address: Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom. Phone: (44 1225) 826 318. Fax: (44 1225) 826 779. E-mail:
bssdjc{at}bath.ac.uk.
Journal of Bacteriology, February 2002, p. 1204-1208, Vol. 184, No. 4
0021-9193/01/$04.00+0 DOI: 10.1128/jb.184.4.1204-1208.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.
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