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Journal of Bacteriology, October 2003, p. 5891-5896, Vol. 185, No. 19
0021-9193/03/$08.00+0 DOI: 10.1128/JB.185.19.5891-5896.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.
Regulation of fur Expression by RpoS and Fur in Vibrio vulnificus
Hyun-Jung Lee,1 Kyung-Je Park,1 Ah Young Lee,2 Sung Goo Park,2 Byoung Chul Park,2 Kyu-Ho Lee,1 and Soon-Jung Park3*
Department of Environmental Science, Hankuk University of Foreign StudiesYongin,1
Proteome Analysis Laboratory, KRIBB, Daejeon,2
Department of Parasitology and Institute of Tropical Medicine, Yonsei University School of Medicine, Seoul, Korea3
Received 24 March 2003/
Accepted 7 July 2003
In a proteomic analysis of rpoS-deficient Vibrio vulnificus versus the wild type, one of the down-regulated proteins in the rpoS mutant strain was identified as a Fur protein, a ferric uptake regulator. The expression of a fur::luxAB fusion was significantly influenced by sigma factor S, the rpoS gene product, and positively regulated by Fur under iron-limited conditions.
* Corresponding author. Mailing address: Department of Parasitology, Yonsei University School of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 152-750, Korea. Phone: 82-2-361-5295. Fax: 82-2-363-8676. E-mail:
sjpark615{at}yumc.yonsei.ac.kr.
Journal of Bacteriology, October 2003, p. 5891-5896, Vol. 185, No. 19
0021-9193/03/$08.00+0 DOI: 10.1128/JB.185.19.5891-5896.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.
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