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Journal of Bacteriology, May 2003, p. 2967-2971, Vol. 185, No. 9
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.9.2967-2971.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Isolation of a New Hemimethylated DNA Binding Protein Which Regulates dnaA Gene Expression

Emmanuelle d'Alençon,{dagger} Aziz Taghbalout, Claire Bristow, Renée Kern, Revital Aflalo, and Masamichi Kohiyama*

Institut J. Monod, Université Paris VI-VII, 75251 Paris Cedex 05, France

Received 21 November 2002/ Accepted 10 February 2003

In this report, we show that yccV, a gene of unknown function, encodes a protein having an affinity for a hemimethylated oriC DNA and that the protein negatively controls dnaA gene expression in vivo.


* Corresponding author. Mailing address: Institut J. Monod, Université Paris VI-VII, 2, Place Jussieu, 75251 Paris Cedex 05, France. Phone: 33 1 4427 6948. Fax: 33 1 4427 5716. E-mail: kohiyama{at}ccr.jussieu.fr.

{dagger} Present address: Laboratoire de Pathologie Comparée, UMR5087 INRA-CNRS-Université Montpellier II, 30380 Saint Christol les Ales, France.


Journal of Bacteriology, May 2003, p. 2967-2971, Vol. 185, No. 9
0021-9193/03/$08.00+0     DOI: 10.1128/JB.185.9.2967-2971.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.




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