This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Melnick, J.
Right arrow Articles by Begley, T. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Melnick, J.
Right arrow Articles by Begley, T. P.

 Previous Article  |  Next Article 

Journal of Bacteriology, June 2004, p. 3660-3662, Vol. 186, No. 11
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.11.3660-3662.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Identification of the Two Missing Bacterial Genes Involved in Thiamine Salvage: Thiamine Pyrophosphokinase and Thiamine Kinase

Jonathan Melnick,1 Ewa Lis,1 Joo-Heon Park,1 Cynthia Kinsland,1 Hirotada Mori,2 Tomoya Baba,3 John Perkins,4 Ghislain Schyns,4 Olga Vassieva,5 Andrei Osterman,5 and Tadhg P. Begley1*

Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853,1 Nara Institute of Science and Technology, Ikoma, Nara 630-0101,2 Institute of Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0035, Japan,3 Abteilung VFB, Roche Vitamins Ltd., CH-4070 Basel, Switzerland,4 Integrated Genomics, Chicago, Illinois 606125

Received 5 September 2003/ Accepted 17 February 2004

The genes encoding thiamine kinase in Escherichia coli (ycfN) and thiamine pyrophosphokinase in Bacillus subtilis (yloS) have been identified. This study completes the identification of the thiamine salvage enzymes in bacteria.

* Corresponding author. Mailing address: Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853. Phone: (607) 255-7133. Fax: (607) 255-4137. E-mail: tpb2{at}cornell.edu.

Journal of Bacteriology, June 2004, p. 3660-3662, Vol. 186, No. 11
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.11.3660-3662.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Eudes, A., Erkens, G. B., Slotboom, D. J., Rodionov, D. A., Naponelli, V., Hanson, A. D. (2008). Identification of Genes Encoding the Folate- and Thiamine-Binding Membrane Proteins in Firmicutes. J. Bacteriol. 190: 7591-7594 [Abstract] [Full Text]  
  • Zayas, C. L., Claas, K., Escalante-Semerena, J. C. (2007). The CbiB Protein of Salmonella enterica Is an Integral Membrane Protein Involved in the Last Step of the De Novo Corrin Ring Biosynthetic Pathway. J. Bacteriol. 189: 7697-7708 [Abstract] [Full Text]  
  • Otte, M. M., Woodson, J. D., Escalante-Semerena, J. C. (2007). The Thiamine Kinase (YcfN) Enzyme Plays a Minor but Significant Role in Cobinamide Salvaging in Salmonella enterica. J. Bacteriol. 189: 7310-7315 [Abstract] [Full Text]  
  • Karunakaran, R., Ebert, K., Harvey, S., Leonard, M. E., Ramachandran, V., Poole, P. S. (2006). Thiamine Is Synthesized by a Salvage Pathway in Rhizobium leguminosarum bv. viciae Strain 3841.. J. Bacteriol. 188: 6661-6668 [Abstract] [Full Text]  
  • Schyns, G., Potot, S., Geng, Y., Barbosa, T. M., Henriques, A., Perkins, J. B. (2005). Isolation and Characterization of New Thiamine-Deregulated Mutants of Bacillus subtilis. J. Bacteriol. 187: 8127-8136 [Abstract] [Full Text]  
  • Kitagawa, M., Ara, T., Arifuzzaman, M., Ioka-Nakamichi, T., Inamoto, E., Toyonaga, H., Mori, H. (2005). Complete set of ORF clones of Escherichia coli ASKA library (A Complete Set of E. coli K-12 ORF Archive): Unique Resources for Biological Research. DNA Res 12: 291-299 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»