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Journal of Bacteriology, September 2004, p. 6327-6331, Vol. 186, No. 18
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.18.6327-6331.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Biofilm Mode of Growth of Streptococcus intermedius Favored by a Competence-Stimulating Signaling Peptide

Fernanda C. Petersen,* Daniele Pecharki, and Anne A. Scheie

Department of Oral Biology, Faculty of Dentistry, University of Oslo, Blindern, Oslo, Norway

Received 5 April 2004/ Accepted 15 June 2004

Gram-positive and gram-negative bacteria use quorum sensing to coordinate population behavior. In several streptococci, quorum sensing mediated by competence-stimulating peptides (CSP) is associated with development of competence for transformation. We show here that a synthetic CSP favored the biofilm mode of growth of Streptococcus intermedius without affecting the rate of culture growth.


* Corresponding author. Mailing address: Department of Oral Biology, Faculty of Dentistry, University of Oslo, P.O. Box 1052, Blindern, N0316 Oslo, Norway. Phone: 47 22840352. Fax: 47 22840302. E-mail: cpaiva{at}odont.uio.no.


Journal of Bacteriology, September 2004, p. 6327-6331, Vol. 186, No. 18
0021-9193/04/$08.00+0     DOI: 10.1128/JB.186.18.6327-6331.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.




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