This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Beaumont, H. J. E.
Right arrow Articles by van Spanning, R. J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beaumont, H. J. E.
Right arrow Articles by van Spanning, R. J. M.

 Previous Article  |  Next Article 

Journal of Bacteriology, October 2005, p. 6849-6851, Vol. 187, No. 19
0021-9193/05/$08.00+0     doi:10.1128/JB.187.19.6849-6851.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Novel nirK Cluster Genes in Nitrosomonas europaea Are Required for NirK-Dependent Tolerance to Nitrite

Hubertus J. E. Beaumont,* Sylvia I. Lens, Hans V. Westerhoff, and Rob J. M. van Spanning

BioCentrum Amsterdam, Department of Molecular Cell Physiology, Vrije Universiteit, de Boelelaan 1087, NL-1081 HV Amsterdam, The Netherlands

Received 5 June 2005/ Accepted 20 July 2005

Nitrite reductase (NirK) of Nitrosomonas europaea confers tolerance to nitrite (NO2–). The nirK gene is clustered with three genes of unknown physiological function: ncgABC. At present, this organization is unique to nitrifying bacteria. Here we report that the ncgABC gene products facilitate NirK-dependent NO2– tolerance by reversing the negative physiological effect that is associated with the activity of NirK in their absence. We hypothesize that the ncg gene products are involved in the detoxification of nitric oxide that is produced by NirK.

* Corresponding author. Present address: Evolutionary Genetics and Microbial Ecology Laboratory, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand. Phone: (64) 9 373 7599, ext. 82777. Fax: (64) 9 373 7416. E-mail: h.beaumont{at}auckland.ac.nz.

Journal of Bacteriology, October 2005, p. 6849-6851, Vol. 187, No. 19
0021-9193/05/$08.00+0     doi:10.1128/JB.187.19.6849-6851.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Klotz, M. G., Arp, D. J., Chain, P. S. G., El-Sheikh, A. F., Hauser, L. J., Hommes, N. G., Larimer, F. W., Malfatti, S. A., Norton, J. M., Poret-Peterson, A. T., Vergez, L. M., Ward, B. B. (2006). Complete Genome Sequence of the Marine, Chemolithoautotrophic, Ammonia-Oxidizing Bacterium Nitrosococcus oceani ATCC 19707. Appl. Environ. Microbiol. 72: 6299-6315 [Abstract] [Full Text]  
  • Cho, C. M.-H., Yan, T., Liu, X., Wu, L., Zhou, J., Stein, L. Y. (2006). Transcriptome of a Nitrosomonas europaea Mutant with a Disrupted Nitrite Reductase Gene (nirK).. Appl. Environ. Microbiol. 72: 4450-4454 [Abstract] [Full Text]  
  • Starkenburg, S. R., Chain, P. S. G., Sayavedra-Soto, L. A., Hauser, L., Land, M. L., Larimer, F. W., Malfatti, S. A., Klotz, M. G., Bottomley, P. J., Arp, D. J., Hickey, W. J. (2006). Genome Sequence of the Chemolithoautotrophic Nitrite-Oxidizing Bacterium Nitrobacter winogradskyi Nb-255.. Appl. Environ. Microbiol. 72: 2050-2063 [Abstract] [Full Text]  
  • Choi, P. S., Naal, Z., Moore, C., Casado-Rivera, E., Abruna, H. D., Helmann, J. D., Shapleigh, J. P. (2006). Assessing the impact of denitrifier-produced nitric oxide on other bacteria.. Appl. Environ. Microbiol. 72: 2200-2205 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»