This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rhee, J. E.
Right arrow Articles by Choi, S. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rhee, J. E.
Right arrow Articles by Choi, S. H.

 Previous Article  |  Next Article 

Journal of Bacteriology, November 2005, p. 7870-7875, Vol. 187, No. 22
0021-9193/05/$08.00+0     doi:10.1128/JB.187.22.7870-7875.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

CadC Activates pH-Dependent Expression of the Vibrio vulnificus cadBA Operon at a Distance through Direct Binding to an Upstream Region

Jee Eun Rhee,1 Kun-Soo Kim,2 and Sang Ho Choi1*

Department of Food Science and Technology, School of Agricultural Biotechnology, and Center for Agricultural Biomaterials, Seoul National University, Seoul 151-742,1 Department of Life Science, Sogang University, Seoul 121-742, South Korea2

Received 12 June 2005/ Accepted 5 September 2005

The Vibrio vulnificus cadBA genes were transcribed as a transcriptional operon by a single promoter, PcadBA, which was activated by CadC in a pH-dependent manner. A direct interaction between CadC and the PcadBA DNA was demonstrated, and a CadC binding site centered at –233.5 was mapped by deletion analyses of PcadBA and confirmed by a DNase I protection assay.

* Corresponding author. Mailing address: Department of Food Science and Technology, School of Agricultural Biotechnology, Center for Agricultural Biomaterials, Seoul National University, Seoul 151-742, South Korea. Phone: 82-2-880-4857. Fax: 82-2-873-5095. E-mail: choish{at}snu.ac.kr.

Journal of Bacteriology, November 2005, p. 7870-7875, Vol. 187, No. 22
0021-9193/05/$08.00+0     doi:10.1128/JB.187.22.7870-7875.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Jones, M. K., Oliver, J. D. (2009). Vibrio vulnificus: Disease and Pathogenesis. Infect. Immun. 77: 1723-1733 [Full Text]  
  • Oh, M. H., Lee, S. M., Lee, D. H., Choi, S. H. (2009). Regulation of the Vibrio vulnificus hupA Gene by Temperature Alteration and Cyclic AMP Receptor Protein and Evaluation of Its Role in Virulence. Infect. Immun. 77: 1208-1215 [Abstract] [Full Text]  
  • Lee, D. H., Jeong, H. S., Jeong, H. G., Kim, K. M., Kim, H., Choi, S. H. (2008). A Consensus Sequence for Binding of SmcR, a Vibrio vulnificus LuxR Homologue, and Genome-wide Identification of the SmcR Regulon. J. Biol. Chem. 283: 23610-23618 [Abstract] [Full Text]  
  • Lee, Y. H., Kim, J. H., Bang, I. S., Park, Y. K. (2008). The Membrane-Bound Transcriptional Regulator CadC Is Activated by Proteolytic Cleavage in Response to Acid Stress. J. Bacteriol. 190: 5120-5126 [Abstract] [Full Text]  
  • Jeong, H. G., Choi, S. H. (2008). Evidence that AphB, Essential for the Virulence of Vibrio vulnificus, Is a Global Regulator. J. Bacteriol. 190: 3768-3773 [Abstract] [Full Text]  
  • Lee, Y. H., Kim, B. H., Kim, J. H., Yoon, W. S., Bang, S. H., Park, Y. K. (2007). CadC Has a Global Translational Effect during Acid Adaptation in Salmonella enterica Serovar Typhimurium. J. Bacteriol. 189: 2417-2425 [Abstract] [Full Text]  
  • Kim, J.-S., Choi, S. H., Lee, J. K. (2006). Lysine Decarboxylase Expression by Vibrio vulnificus Is Induced by SoxR in Response to Superoxide Stress. J. Bacteriol. 188: 8586-8592 [Abstract] [Full Text]  
  • Rhee, J. E., Jeong, H. G., Lee, J. H., Choi, S. H. (2006). AphB Influences Acid Tolerance of Vibrio vulnificus by Activating Expression of the Positive Regulator CadC.. J. Bacteriol. 188: 6490-6497 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»