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Journal of Bacteriology, September 2006, p. 6709-6713, Vol. 188, No. 18
0021-9193/06/$08.00+0 doi:10.1128/JB.00680-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.
Department of Chemistry and Biochemistry, 160 Hughes Hall, Miami University, Oxford, Ohio 45056
Received 12 May 2006/ Accepted 4 July 2006
DNA microarrays were used to probe the transcriptional response of Escherichia coli to N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Fifty-five transcripts were significantly up-regulated, including all of the genes that are regulated by Zur and many that are regulated by Fur. In the same TPEN-treated cells, 46 transcripts were significantly down-regulated.
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