This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kuban, W.
Right arrow Articles by Fijalkowska, I. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kuban, W.
Right arrow Articles by Fijalkowska, I. J.

 Previous Article  |  Next Article 

Journal of Bacteriology, November 2006, p. 7977-7980, Vol. 188, No. 22
0021-9193/06/$08.00+0     doi:10.1128/JB.01088-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Role of DNA Polymerase IV in Escherichia coli SOS Mutator Activity{triangledown}

Wojciech Kuban,1 Magdalena Banach-Orlowska,1 Roel M. Schaaper,2 Piotr Jonczyk,1 and Iwona J. Fijalkowska1*

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02 106 Warsaw, Poland,1 Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 277092

Received 22 July 2006/ Accepted 8 September 2006

Constitutive expression of the SOS regulon in Escherichia coli recA730 strains leads to a mutator phenotype (SOS mutator) that is dependent on DNA polymerase V (umuDC gene product). Here we show that a significant fraction of this effect also requires DNA polymerase IV (dinB gene product).

* Corresponding author. Mailing address: Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5A 02 106 Warsaw, Poland. Phone: (48) 22-592-1113. Fax: (48) 22-658-4636. E-mail: iwonaf{at}ibb.waw.pl.

{triangledown} Published ahead of print on 15 September 2006.

Journal of Bacteriology, November 2006, p. 7977-7980, Vol. 188, No. 22
0021-9193/06/$08.00+0     doi:10.1128/JB.01088-06
Copyright © 2006, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Heisig, P. (2009). Type II topoisomerases--inhibitors, repair mechanisms and mutations. Mutagenesis 24: 465-469 [Abstract] [Full Text]  
  • Petrosino, J. F., Galhardo, R. S., Morales, L. D., Rosenberg, S. M. (2009). Stress-Induced {beta}-Lactam Antibiotic Resistance Mutation and Sequences of Stationary-Phase Mutations in the Escherichia coli Chromosome. J. Bacteriol. 191: 5881-5889 [Abstract] [Full Text]  
  • Galhardo, R. S., Do, R., Yamada, M., Friedberg, E. C., Hastings, P. J., Nohmi, T., Rosenberg, S. M. (2009). DinB Upregulation Is the Sole Role of the SOS Response in Stress-Induced Mutagenesis in Escherichia coli. Genetics 182: 55-68 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»