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Journal of Bacteriology, January 2007, p. 269-271, Vol. 189, No. 1
0021-9193/07/$08.00+0     doi:10.1128/JB.01456-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Linker Regions of the RhaS and RhaR Proteins{triangledown}

Ana Kolin,1 Visnja Jevtic,1 Liskin Swint-Kruse,2 and Susan M. Egan1*

Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045,1 Department of Biochemistry and Molecular Biology, MS 3030, The University of Kansas Medical Center, Kansas City, Kansas 661602

Received 14 September 2006/ Accepted 13 October 2006

Substitutions within the interdomain linkers of the AraC/XylS family proteins RhaS and RhaR were tested to determine whether side chain identity or linker structure was required for function. Neither was found crucial, suggesting that the linkers do not play a direct role in activation, but rather simply connect the two domains.

* Corresponding author. Mailing address: Department of Molecular Biosciences, 1200 Sunnyside Ave., University of Kansas, Lawrence, KS 66045. Phone: (785) 864-4294. Fax: (785) 864-5294. E-mail: sme{at}ku.edu.

{triangledown} Published ahead of print on 27 October 2006.

Journal of Bacteriology, January 2007, p. 269-271, Vol. 189, No. 1
0021-9193/07/$08.00+0     doi:10.1128/JB.01456-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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