This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shimomura, H.
Right arrow Articles by Hirai, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shimomura, H.
Right arrow Articles by Hirai, Y.

 Previous Article  |  Next Article 

Journal of Bacteriology, July 2007, p. 4960-4963, Vol. 189, No. 13
0021-9193/07/$08.00+0     doi:10.1128/JB.00272-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Conversion of Flavodoxin from Holoenzyme to Apoprotein during Growth Phase Changes in Helicobacter pylori{triangledown}

Hirofumi Shimomura,1* Shunji Hayashi,1 Kenji Yokota,2 Keiji Oguma,2 and Yoshikazu Hirai1

Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, Tochigi 329-0498,1 Department of Bacteriology, Graduate School of Medicine, Dentistry and Pharmacology, Okayama University, Okayama 700-8558, Japan2

Received 19 February 2007/ Accepted 12 April 2007

The catabolic pathway for flavodoxin has yet to be clarified for any bacterial species. In this study, we found that the flavin mononucleotide in the flavodoxin of Helicobacter pylori is degraded to riboflavin via the phosphomonoesterase activity of class C acid phosphatase. The result is a conversion of holoflavodoxin to apoflavodoxin.


* Corresponding author. Mailing address: Division of Bacteriology, Department of Infection and Immunity, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan. Phone: 81-285-58-7332. Fax: 81-285-44-1175. E-mail: shimo{at}jichi.ac.jp

{triangledown} Published ahead of print on 20 April 2007.


Journal of Bacteriology, July 2007, p. 4960-4963, Vol. 189, No. 13
0021-9193/07/$08.00+0     doi:10.1128/JB.00272-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.