This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hosking, E. R.
Right arrow Articles by Manson, M. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hosking, E. R.
Right arrow Articles by Manson, M. D.

 Previous Article  |  Next Article 

Journal of Bacteriology, August 2008, p. 5517-5521, Vol. 190, No. 15
0021-9193/08/$08.00+0     doi:10.1128/JB.00407-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Clusters of Charged Residues at the C Terminus of MotA and N Terminus of MotB Are Important for Function of the Escherichia coli Flagellar Motor {triangledown}

Edan R. Hosking{dagger} and Michael D. Manson*

Department of Biology, Texas A&M University, College Station, Texas 77843-3258

Received 22 March 2008/ Accepted 28 April 2008

MotA contains a conserved C-terminal cluster of negatively charged residues, and MotB contains a conserved N-terminal cluster of positively charged residues. Charge-altering mutations affecting these residues impair motility but do not diminish Mot protein levels. The motility defects are reversed by second-site mutations targeting the same or partner protein.

* Corresponding author. Mailing address: Department of Biology, Texas A&M University, College Station, TX 77843-3258. Phone: (979) 845-5158. Fax: (979) 845-2891. E-mail: mike{at}mail.bio.tamu.edu

{triangledown} Published ahead of print on 9 May 2008.

{dagger} Present address: Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109.

Journal of Bacteriology, August 2008, p. 5517-5521, Vol. 190, No. 15
0021-9193/08/$08.00+0     doi:10.1128/JB.00407-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Che, Y.-S., Nakamura, S., Kojima, S., Kami-ike, N., Namba, K., Minamino, T. (2008). Suppressor Analysis of the MotB(D33E) Mutation To Probe Bacterial Flagellar Motor Dynamics Coupled with Proton Translocation. J. Bacteriol. 190: 6660-6667 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»