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Journal of Bacteriology, September 2008, p. 6264-6270, Vol. 190, No. 18
0021-9193/08/$08.00+0     doi:10.1128/JB.00740-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Identification of a {sigma}B-Dependent Small Noncoding RNA in Listeria monocytogenes{triangledown} ,{dagger}

Jesper Sejrup Nielsen, Anders Steno Olsen, Mette Bonde, Poul Valentin-Hansen, and Birgitte H. Kallipolitis*

Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark

Received 24 May 2008/ Accepted 30 June 2008

In Listeria monocytogenes, the alternative sigma factor {sigma}B plays important roles in stress tolerance and virulence. Here, we present the identification of SbrA, a novel small noncoding RNA that is produced in a {sigma}B-dependent manner. This finding adds the {sigma}B regulon to the growing list of stress-induced regulatory circuits that include small noncoding RNAs.

* Corresponding author. Mailing address: Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark. Phone: 45 6550 2372. Fax: 45 6550 2467. E-mail: bhk{at}bmb.sdu.dk

{triangledown} Published ahead of print on 11 July 2008.

{dagger} Supplemental material for this article may be found at http://jb.asm.org/.

Journal of Bacteriology, September 2008, p. 6264-6270, Vol. 190, No. 18
0021-9193/08/$08.00+0     doi:10.1128/JB.00740-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



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