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 Previous Article

Journal of Bacteriology, November 2008, p. 7308-7313, Vol. 190, No. 21
0021-9193/08/$08.00+0     doi:10.1128/JB.00820-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Box C/D RNA-Guided 2'-O Methylations and the Intron of tRNATrp Are Not Essential for the Viability of Haloferax volcanii{triangledown}

Archi Joardar, Priyatansh Gurha, Geena Skariah, and Ramesh Gupta*

Department of Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, Illinois 62901-4413

Received 10 June 2008/ Accepted 23 August 2008

Deleting the box C/D RNA-containing intron in the Haloferax volcanii tRNATrp gene abolishes RNA-guided 2'-O methylations of C34 and U39 residues of tRNATrp. However, this deletion does not affect growth under standard conditions.

* Corresponding author. Mailing address: Department of Biochemistry and Molecular Biology, Southern Illinois University, 1245 Lincoln Drive, Carbondale, IL 62901-4413. Phone: (618) 453-6466. Fax: (618) 453-6440. E-mail: rgupta{at}siumed.edu

{triangledown} Published ahead of print on 29 August 2008.

Journal of Bacteriology, November 2008, p. 7308-7313, Vol. 190, No. 21
0021-9193/08/$08.00+0     doi:10.1128/JB.00820-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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