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Journal of Bacteriology, February 2009, p. 1106-1110, Vol. 191, No. 3
0021-9193/09/$08.00+0     doi:10.1128/JB.00599-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Genome-Wide Identification of H-NS-Controlled, Temperature-Regulated Genes in Escherichia coli K-12{triangledown} ,{dagger}

Christine A. White-Ziegler* and Talya R. Davis{ddagger}

Department of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts

Received 30 April 2008/ Accepted 10 November 2008

DNA microarrays demonstrate that H-NS controls 69% of the temperature regulated genes in Escherichia coli K-12. H-NS is shown to be a common regulator of multiple iron and other nutrient acquisition systems preferentially expressed at 37°C and of general stress response, biofilm formation, and cold shock genes highly expressed at 23°C.

* Corresponding author. Mailing address: Department of Biological Sciences, Smith College, Northampton, MA 01063. Phone: (413) 585-3815. Fax: (413) 585-3786. E-mail: cwhitezi{at}smith.edu

{triangledown} Published ahead of print on 14 November 2008.

{dagger} Supplemental material for this article may be found at http://jb.asm.org/.

{ddagger} Present address: Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111.

Journal of Bacteriology, February 2009, p. 1106-1110, Vol. 191, No. 3
0021-9193/09/$08.00+0     doi:10.1128/JB.00599-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • White-Ziegler, C. A., Davis, T. R. (2009). Genome-Wide Identification of H-NS-Controlled, Temperature-Regulated Genes in Escherichia coli K-12. J. Bacteriol. 191: 1106-1110 [Abstract] [Full Text]  


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