J. Bacteriol. doi:10.1128/JB.00065-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.
Mobilization of the incQ Plasmid R300B with a Chromosomal Conjugation System in Salmonella Typhi
Stephen Baker*,
Derek Pickard,
Sally Whitehead,
Jeremy Farrar,
and
Gordon Dougan
The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom; Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
* To whom correspondence should be addressed. Email:
sbaker{at}oucru.org.
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Abstract |
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Salmonella Pathogenicity Island Seven (SPI-7) in Salmonella enterica serovar Typhi (S. Typhi) appears to be related to other genomic islands. Evidence suggests that SPI-7 is susceptible to spontaneous circularisation, loss and transposition. Here, we demonstrate that a region within SPI-7 has the ability mobilize the small incQ plasmid R300B.