This Article Full Text (PDF) Other Versions of this Article: JB.00348-07v1 189/17/6276    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Xu, H. Articles by Miao, V. Search for Related Content PubMed PubMed Citation Articles by Xu, H. Articles by Miao, V.

 Previous Article  |  Next Article 

J. Bacteriol. doi:10.1128/JB.00348-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Molecular characterization of class 3 integrons from Delftia spp

Department of Microbiology and Immunology, University of British Columbia, Vancouver BC V6T 1Z3 Canada

^* To whom correspondence should be addressed. Email: vmiao{at}telus.net.

	Abstract

Two environmental strains, Delftia acidovorans C17 and Delftia tsuruhatensis A90, were found to carry Class 3 integrons, which have seldom been reported and then only from pathogens in which they are associated with antibiotic resistance genes. The Delftia integrons were comprised of a highly conserved Class 3 integrase gene, upstream and oppositely oriented from a set of three or four gene cassettes that encoded unidentified functions. The A90 integron in A90 had one more gene cassette than the C17 integron, but the two were otherwise the same; furthermore, they were located within regions of sequence identity in both strains and linked to chromosomal genes. A screen of other Delftia and related strains did not reveal the presence of additional Class 3 integrons. The observations suggest that these integrons were horizontally transferred into Delftia as part of a larger region, and reside as chromosomal elements that probably predate transposon dissemination, as has been proposed for certain Class I integrons.

This article has been cited by other articles:

• Gillings, M., Boucher, Y., Labbate, M., Holmes, A., Krishnan, S., Holley, M., Stokes, H. W. (2008). The Evolution of Class 1 Integrons and the Rise of Antibiotic Resistance. J. Bacteriol. 190: 5095-5100 [Abstract] [Full Text]