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J. Bacteriol. doi:10.1128/JB.00700-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Agr interference between clinical Staphylococcus aureus strains in an insect model of virulence

Dept of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK; Peter Medawar Building, Nuffield Dept. of Medicine, University of Oxford, Oxford OX1 3SY, UK; Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand; Dept. of Zoology, University of Oxford, Oxford, OX1 3PS, UK

^* To whom correspondence should be addressed. Email: ruth.massey{at}zoo.ox.ac.uk.

	Abstract

Repression of virulence by Staphylococcus aureus strains from different Agr groups has been demonstrated in vitro, and is proposed as a means of competitive interference. Here, using the insect Manduca sexta we show for the first time that this interference also occurs in vivo within a mixed population.

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