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J. Bacteriol. doi:10.1128/JB.00705-07
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

The Two-Component Response Regulator RcsB Regulates Type 1 Piliation in Escherichia coli

William R. Schwan, Satoshi Shibata, Shin-Ichi Aizawa, and Alan J. Wolfe*

Department of Microbiology, University of Wisconsin-La Crosse, La Crosse, WI 54601; Department of Life Sciences, Prefectural University of Hiroshima, 562 Nanatsuka, Shobara, Hiroshima 727-0023, Japan; CREST "Soft Nano-Machine Project", Innovation Plaza Hiroshima, 3-10-23 Kagamiyama, Higashi-Hiroshima 739-0046; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA

* To whom correspondence should be addressed. Email: awolfe{at}lumc.edu.


   Abstract

The ability of Escherichia coli cells to produce type 1 pili depends upon the orientation of the fimA promoter. The orientation depends upon the ratios of the FimB and FimE recombinases. Here, we report that the two-component response regulator RcsB influences the piliation state by controlling fimB and fimE transcription.




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