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J. Bacteriol. doi:10.1128/JB.00820-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

A novel conserved assembly factor of the bacterial flagellum

Institute of Genetics, Forschungszentrum Karlsruhe, Karlsruhe, Germany

^* To whom correspondence should be addressed. Email: peter.uetz{at}itg.fzk.de.

	Abstract

TP0658 and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum, FliC in most other species). Mutants of orthologs in B. subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin similar to FliS suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum.

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