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J. Bacteriol. doi:10.1128/JB.01061-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

RamB, the transcriptional regulator of acetate metabolism in Corynebacterium glutamicum is subject to regulation by RamA and RamB

Dept. Microbiology and Biotechnology, University of Ulm, 89069 Ulm, and Institute of Biotechnology 1, Research Center Jülich, D-52425 Jülich, Germany

^* To whom correspondence should be addressed. Email: bernhard.eikmanns{at}uni-ulm.de.

	Abstract

In Corynebacterium glutamicum, the transcriptional regulator RamB negatively controls the expression of genes involved in acetate metabolism. Here we show that RamB represses its own expression by direct interaction with a 13-bp motif in the ramB promoter region. Additionally, ramB expression is subject to carbon source-dependent, positive control by RamA.

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